Mfn1 CLIA Kit for Rat(Rattus norvegicus) | EIAab.comMfn1 CLIA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Mfn1(Gene name) > Rat

Mfn1 (Gene name),

Mitofusin-1 (Protein name ), MFN1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mfn1(Fzo1b);

Protein name:

Mitofusin-1;

Alternative:

Transmembrane GTPase MFN1;Mitochondrial transmembrane GTPase FZO1B;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Forms homomultimers and heteromultimers with MFN2. Multimerization, which is probably mediated by the coiled coil region, may play an essential role in mitochondrion fusion. Participates in a high molecular weight multiprotein complex.

Function:

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.

Subcellular Location:

Mitochondrion outer membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

741

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

741:

EIDQLEKIQN | NSKLLRNKAV | QLERELENFS | KQFLHPSSGE | S

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.160939

KEGG:

rno:192647

SMR:

Q8R4Z9

Pfam:

PF00350

Uniprot:

Q8R4Z9

FOR

ELISA Kit for Rat Mitofusin-1

Cat.:

E15253h

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MSDS:

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Packing:

96T

ELISA Kit for Rat Mitofusin-1

Cat.:

E15253m

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MSDS:

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Packing:

96T

ELISA Kit for Rat Mitofusin-1

Cat.:

E15253r

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Packing:

96T

CLIA Kit for Rat Mitofusin-1

Cat.:

U15253r

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MSDS:

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Packing:

96T

CLIA Kit for Rat Mitofusin-1

Cat.:

U15253m

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Mitofusin-1

Cat.:

U15253h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Mitofusin-1

Cat.:

P15253Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Mitofusin-1

Cat.:

P15253Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat Mitofusin-1

Cat.:

P15253Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Mitofusin-1

Protein for Rat Mitofusin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Two mitofusin proteins, mammalian homologues of FZO, with distinct functions are both required for mitochondrial fusion."
Eura Y. , Ishihara N. , Yokota S. , Mihara K.
J. Biochem.134:333-344(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MULTIMERIZATION;MUTAGENESIS OF LYS-88
tissue: Liver.
2.

"Regulation of mitochondrial morphology by membrane potential, and DRP1-dependent division and FZO1-dependent fusion reaction in mammalian cells."
Ishihara N. , Jofuku A. , Eura Y. , Mihara K.
Biochem. Biophys. Res. Commun.301:891-898(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
3.

"Stage-specific enhanced expression of mitochondrial fusion and fission factors during spermatogenesis in rat testis."
Honda S. , Hirose S.
Biochem. Biophys. Res. Commun.311:424-432(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
4.

"Identification of a novel protein that regulates mitochondrial fusion by modulating mitofusin (Mfn) protein function."
Eura Y. , Ishihara N. , Oka T. , Mihara K.
J. Cell Sci.119:4913-4925(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VAT1

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